n. A hole full of deep mud or mire; a quagmire of considerable depth and comparatively small extent of surface.n. (slö), A marshy hollow; a reedy pond; also, a long shallow ravine, or open creek, which becomes partly or wholly dry in summer.n. Synonyms Swamp, etc. See marsh.n. The skin of a serpent, usually the cast skin; also, any part of an animal that is naturally shed or molted; a cast; an exuvium.n. In pathology, a dead part of tissue which separates from the surrounding living tissue, and is cast off in the act of sloughing.n. A husk.To come off as a slough: often with off.To cast off a slough.To cast off as a slough; in pathology, to throw off, as a dead mass from an ulcer or a wound.A Middle English variant of slow.