This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

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adj. Capable of soothing or eliminating pain.

adj. Relaxing: anodyne novels about country life.

n. A medicine, such as aspirin, that relieves pain.

n. A source of soothing comfort.

n. Any medicine or other agent that relieves pain.

n. A source of relaxation or comfort.

adj. Serving to assuage pain; soothing.

n. Any medicine which allays pain, as an opiate or narcotic; anything that soothes disturbed feelings.

Having power to relieve pain; hence, soothing to the feelings.

n. A medicine or drug which relieves pain, as an opiate or a narcotic; hence, figuratively, anything that allays mental pain or distress.

adj. capable of relieving pain

n. a medicine used to relieve pain

"HoF II was designed by the Taylor Morrison company, a home builder specializing in anodyne subdevelopmental housing in the Southwest."

moderating   

hoffmann's anodyne   

anodynous    anodynia   

soothing   

depressant    vermifuge    sedative    nepenthe    diuretic    painkiller    aphrodisiac    tonic    philter    meperidine