Aphidicolin

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Wiktionary, Creative Commons Attribution/Share-Alike License
  • n. A tetracyclic diterpene antibiotic with antiviral and antimitotical properties.
  • Word Usage
    "Several studies have predicted that some CNV and nonrecurring copy number changes (CNC) in cancer cell lines, which are induced by aphidicolin or occur in some cases of Duchenne muscular dystrophy, Smith-Magenis syndrome, and Pelizaeus-Merzbacher disease, originate from nonhomologous end joining, fork stalling and template switching, or microhomology/microsatellite-induced replication mechanisms"