The American Heritage® Dictionary of the English Language, 4th Edition
n. A drug administered orally in the treatment of depression and as an aid in the cessation of tobacco smoking, thought to inhibit neuronal uptake of serotonin, norepinephrine, and dopamine in the central nervous system.
n. An aminoketone antidepressant that acts as a norepinephrine and dopamine reuptake inhibitor and nicotinic antagonist.
Word Usage
"While some antidepressants actually increase weight, at least one—called bupropion (Wellbutrin)—has been shown to be effective for weight loss by influencing levels of norepinephrine (the fight-or-flight neurochemical), as well as increasing the pleasure-seeking dopamine."