This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

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n. Weight loss, wasting of muscle, loss of appetite, and general debility that can occur during a chronic disease.

n. A systemic wasting of muscle tissue, with or without loss of fat mass, that accompanies a chronic disease

n. A condition of ill health and impairment of nutrition due to impoverishment of the blood, esp. when caused by a specific morbid process (as cancer or tubercle).

n. Same as cachexy.

n. any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease

"About half of all cancer patients eventually suffer serious weight loss and malnutrition, a wasting syndrome called cachexia where they don't just lose excess fat but vital muscle."

cachexy   

feebleness    infirmity    frailty    frailness    debility