n. A destructive disease of bone, causing a friable condition and worm-eaten appearance, attended with suppuration. It is probable that several distinct pathological processes lead to this morbid condition.n. A disease of the teeth, resulting in the disintegration of their substance and the formation of cavities. In man and carnivorous animals it is supposed to be caused by one of the bacteria, Leptothrix buccalis. See Leptothrix.n. In botany, decay of the walls of the cells and vessels.