To make domestic; accustom to remain much at home: as, to domesticate one's self.To make an inmate of a household; associate in family life; hence, to make intimate or cause to become familiar, as if at home.To convert to domestic uses, as wild animals or plants; tame or bring under control or cultivation; reclaim from a state of nature.To live much at home; lead a quiet home life; become a member of a family circle.