n. A state of feeling unwell or unhappy; a feeling of emotional and mental discomfort and suffering from restlessness, malaise, depression or anxiety.
the GNU version of the Collaborative International Dictionary of English
n. Impatience under affliction; morbid restlessness; dissatisfaction; the fidgets.
The Century Dictionary and Cyclopedia
n. In pathology, impatience under affliction; a state of dissatisfaction, restlessness, fidgeting, or inquietude.
WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
n. abnormal depression and discontent
Word Usage
"Gender identity disorder (GID)/gender dysphoria is a little known but much misunderstood congenital intersex condition, which is clinically diagnosable and treatable."