This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

• Lexulous
• Wordscraper
• Wordosaur

n. The grasping of hands by two people, as in greeting or leave-taking.

n. Computer Science An exchange of signals between two devices when communications begin in order to ensure synchronization.

n. The grasping of hands by two people when greeting or leave-taking

n. An exchange of signals between two devices when communications begin in order to ensure synchronization

n. grasping and shaking a person's hand (as to acknowledge an introduction or to agree on a contract)

"By analogy, a handshake is a warm way to greet a client in business, but rather cold among family members where a hug is more appropriate."

acknowledgment    acknowledgement   

shake hands   

hug    greeting    pat    squeeze    clasp    nod    salutation    congratulation    good-bye    caress