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adj. Of or pertaining to the epitope of a molecule that provokes the most intense immune response

"BenMohamed L, Bertrand G, McNamara CD, Gras-Masse H, Hammer J, et al. (2003) Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity."