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n. Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.

n. Any of a group of enzymes that catalyze the binding of two molecules; synthetase.

n. An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, DNA ligase, an enzyme which creates a phosphate bond between 5′ and 3′ ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells.

"S., and Ciechanover, A. (1983) "Components of ubiquitin-protein ligase system"."

ligate   

dna ligase   

thiol    endotoxin    synthetase    moiety    hydrolase    brouhaha    unscratched    cysteine    proteases    anecdotic