This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

• Lexulous
• Wordscraper
• Wordosaur

n. Plural form of megrim.

n. Any of various diseases of animals, especially horses. (More at megrim.)

n. Depression, low spirits, unhappiness.

n. a state of depression

"We call our megrims the melancholy of a sublime soul, the yearnings of an indigestion we denominate yearnings after immortality, nay, sometimes"

depression