The American Heritage® Dictionary of the English Language, 4th Edition
n. A toxic antimetabolite, C20H22N8O5, that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases such as rheumatoid arthritis.
n. An antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases.
WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
n. toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
Word Usage
"An intravenous IV infusion of a medication called methotrexate may be used to abort the pregnancy or may be combined with surgery to ensure the full removal of pregnancy tissues."