the GNU version of the Collaborative International Dictionary of English
n. Abnormal hardness and density of bone.
The Century Dictionary and Cyclopedia
n. The excessive formation of bone-tissue in the Haversian canals and other spaces of bone, so that it becomes denser.
WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
n. abnormal hardening or eburnation of bone
Word Usage
"Likewise, activating mutations of Lrp5 in mice and humans cause osteosclerosis, a high bone mass disorder resulting from increased osteoblast activity"