n. The act of perforating or pricking with a pointed instrument, or a small hole made by it; a small wound, as one made by a needle, prickle, or sting: as, the puncture of a lancet, nail, or pin.n. In zoology, a depressed point or dot, as if punctured; a small depression, as if pricked into a surface; a punctum. See cut under Coscinoptera.To prick; pierce with a sharp point of any kind: as, to puncture the skin.