To disapprove vehemently; contemn strongly; condemn; reject.To abandon to vice or punishment, or to hopeless ruin or destruction. See reprobation, 3.Synonyms To reprehend, censure. See reprobate, a.Disallowed; disapproved; rejected; not enduring proof or trial.Abandoned in sin; morally abandoned; depraved; characteristic of a reprobate.Expressing disapproval or censure; condemnatory.Synonyms profligate, etc. (see abandoned), vitiated, corrupt, hardened, wicked, base, vile, cast away, graceless, shameless.n. One who is very profligate or abandoned; a person given over to sin; one lost to virtue and religion; a wicked, depraved wretch.