n. Injury; mischief; shame; disgrace; dishonor.n. A disposition to thwart and disappoint the wishes of another; ill-will; malevolence; malice; grudge; rancor.n. Chagrin; vexation; ill luck; trouble.n. Synonyms Animosity, Ill-will, Enmity, etc. (see animosity), pique, spleen, defiance. In spite of, Despite, etc. See not-withstanding.To dislike; regard with ill-will.To thwart; cross; mortify; treat maliciously: as, to cut off one's nose to spite one's face.To fill with vexation; offend.