adj. Embedded within and spread throughout and affecting a group, system, body, economy, market, or society as a whole.
adj. Pertaining to an entire organism.
the GNU version of the Collaborative International Dictionary of English
adj. Of or relating to a system; common to a system.
adj. Of or pertaining to the general system, or the body as a whole.
The Century Dictionary and Cyclopedia
Of or pertaining to system or systematization; systematic.
In physiology, pertaining to the body as a whole; somatic; common to a general system; not local: as, systemic circulation.
WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
adj. affecting an entire system
Word Usage
"In 1895, a renowned physician, Sir William Osier, recognized that some forms of lupus involved more than just a rash and actually affected internal organs, and he added the word systemic to the name."