This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

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v. To detach from what secures; unfasten.

v. To cause to leave a tranquil condition; disturb.

v. To unfasten from a fixing

v. To loosen from a fastening; to detach from anything that holds; to unsettle

v. To make fluid; to dissolve.

To make no longer fixed or firm; loosen from any fastening; detach; unsettle: as, to unfix the mind or affections; to unfix bayonets.

To melt; dissolve.

"He attempted to withdraw his hand but Carrigan maintained an unconscious clamp on it, which threw Daniel's free hand into dire confusion: it moved to unfix its imprisoned sibling, but, to its utter horror, found itself established atop Carrigan's wrist in a four-layer embrace that could only be described as intimate."

unfixed    unfixes    unfixing   

unsettle    dissolve    unfasten    loose    detach