This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

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v. To cause to lose affection or loyalty. See Synonyms at estrange.

v. To cause a loss of affection, sympathy or loyalty; to alienate or estrange

v. To alienate or diminish the affection of; to make unfriendly or less friendly; to fill with discontent and unfriendliness.

v. To disturb the functions of; to disorder.

v. To lack affection for; to be alienated from, or indisposed toward; to dislike.

To alienate the affection of; make less friendly; make discontented or unfriendly: as, an attempt was made to disaffect the army.

To lack affection or esteem for; not to affect; dislike; stand aloof from: as, to disaffect society.

To throw into disorder; derange.

v. arouse hostility or indifference in where there had formerly been love, affection, or friendliness

"I understand that sentiment, and while addressing controversial issues may anger a few, not doing so could disaffect a far greater number of people if speaking out would have made a difference in the public understanding of an issue or led to an improved outcome as a result."

disaffected    disaffecting    disaffects   

change    modify    alter   

drift apart    drift away    wean   

disaffection   

disorder    dislike    alienate    displease   

Brecht    Hecht    Select    affect    bedecked    checked    collect    confect    connect    correct