n. A written communication directed or sent to a person at a distance; a letter; a letter missive: used particularly in dignified discourse or in speaking of ancient writings: as, the epistles of Paul, of Pliny, or of Cicero.n. [capitalized] In liturgics, one of the eucharistic lessons, taken, with some exceptions, from an epistolary book of the New Testament and read before the gospel.n. Any kind of harangue or discourse; a communication.To write as a letter; communicate by writing or by an epistle.