This word is acceptable for play in the US & UK dictionaries that are being used in the following games:

• Lexulous
• Wordscraper
• Wordosaur

n. The act of estranging; the act of alienating; alienation.

n. The state of being alien; foreign, non-native.

n. The act of estranging, or the state of being estranged; alienation.

n. The act of estranging, or the state of being estranged, in any sense of that word.

n. the feeling of being alienated from other people

n. separation resulting from hostility

"Academics call it estrangement, but it comes down to the same thing."

isolation   

estrange    estranged   

étrangement   

alienation   

arrangement    rearrangement   

alienation    dissensions    antagonism    schism    antipathy    mistrust    misunderstanding    disaffection    obliteration    disagreement