n. The joint of a finger, especially that between the metacarpal bone and the first phalanx.n. The knee or knee-joint.n. A joint, especially of veal, consisting of the part of the leg called the knee. It is the part of the animal which corresponds to the hock of a horse, or the human heel, together with more or less of the leg above this joint.n. The joint of a plant; a node.n. A joint of cylindrical form, with a pin as axis, as that by which the straps of a hinge are fastened together.n. In ship-building, an acute angle on some of the timbers.n. plural Pieces of metal, usually brass (hence specifically known as brass knuckles), worn by lawless persons over the knuckles to protect them in striking a blow, and also to make a blow more effective. See knuckle-duster.To touch or strike with the knuckle; pommel.To bend the knuckles; hold the knuckles (that is, the hand) close to the ground, in playing marbles: usually with down.To apply one's self earnestly, as to a task; engage vigorously, as in work.To submit, as in a contest; give up; yield.n. A sharply bent loop, as of intestine, especially when imprisoned, as in a hernia.n. In mech., the swinging leaf or hook used for the coupling device in certain automatic car-couplings, particularly in the Janney or M. C. B. (master car-builders') type. A hole is usually provided in the knuckle so that the common link-coupling may be used with it.To apply one's self earnestly.