n. The state of being a master; power of command or control; rule; dominion; sway.n. Ascendancy in war or in competition; the upper hand; superiority; preëminence.n. Expert knowledge or skill; power of using or exercising; dexterity: as, the mastery of an art or science.n. Masterly attainment; the gaining of mastership.n. A contest for superiority.n. A masterly operation or act; a triumph of skill.n. The finding of the magisterium or philosopher's stone; also, the stone itself.