To make foul, turbid, or muddy, as water.To bewilder; perplex.To intoxicate partially; cloud or stupefy, particularly with liquor: as, to muddle one's brains.To spend profitlessly; waste; misuse; fritter: usually with away.To bring into a state of confusion; make a mess of.To mix; stir: as, to muddle chocolate or drinks.To contract filth; become muddy or foul.To become confused, especially from drink.To potter about; wander confusedly.n. A mess; dirty confusion; filth.n. Intellectual confusion; cloudiness; bewilderment.n. A kind of chowder; a pottle made with crackers. See pottle, 2.