n. The act of prostrating, throwing down, or laying flat.n. The act of falling down, or the act of bowing, in humility or adoration; primarily, the act of falling on the face, but the word is now used also for kneeling or bowing in reverence and worship.n. Great depression; dejection: as, a prostration of spirits.n. In medicine, a great loss of strength, which may involve both voluntary and involuntary functions.