To draw up or contract into irregular folds or wrinkles; specifically, in sewing, to gather: often followed by up: as, to pucker cloth in sewing.To become irregularly ridged or wrinkled: as, his face puckered up into a smile; the mouth puckers on eating choke-cherries.n. A drawing or gathering into folds or wrinkles; an irregular folding or wrinkling; a collection of irregularly converging ridges or wrinkles.n. A state of flutter, agitation, or confusion.