n. A blow or calamity; severe trouble or vexation; also, one who or that which troubles or vexes, or ravages or destroys.n. Any epidemic disease of high mortality.n. As an expletive with the article the, used like the devil, the deuce, etc. Compare devil, 7.To vex; harass; trouble; annoy; tease.To infest with disease, calamity, or natural evil of any kind.Synonyms Torment, Worry, etc. (see tease), gall, bore.To afflict.n.